Gianotti-Crosti sounds like a great name for an Italian sports car, instead it is the name of a rash that is often symptomatic with the administration of vaccines, like H1N1 Swine Flu, seasonal flu and others.
One of the most read articles on Ahrcanum is “Swine Flu, Rash Hives and Symptoms” at http://ahrcanum.wordpress.com/2009/10/19/swine-flu-rash-hives-symptoms/ where you can read posts from hundreds of people sharing in having some sort of rash. Included there, is a post from “Good Luck,” who has a two year old grandaughter nicknamed JuneBug who had a horrible rash. The parents opted to give her the H1N1 Swine Flu vaccine with it’s two standard doses. Six, yes Six doctors later it has been identified as Gianotti-Crosti Syndrome.
The rash of Gianotti-Crosti syndrome (GCS) usually has sudden onset and may be associated with an acute infectious illness or immunization. The rash is usually present for 2-4 weeks but can last as long as 4 months. http://emedicine.medscape.com/article/1111108-overview
- Nonrelapsing erythemato-papular dermatitis localized to the face and limbs, lasting about three weeks
- Paracortical hyperplasia of lymph nodes
- Acute hepatitis, usually anicteric, which could last for months and progress to chronic liver disease via, http://www.uptodate.com/patients/content/topic.do?topicKey=~Hol/SXB_qWq_mG
It is most common in Mediterranean countries according to http://www.whonamedit.com/synd.cfm/4051.html. I do not believe so many of the sufferers of this rash have been visiting the Mediterranean on holiday.
While the condition usually resolves spontaneously within about 3 weeks it is listed as a “rare disease” by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Gianotti-Crosti Syndrome, or a subtype of Gianotti-Crosti Syndrome, affects less than 200,000 people in the US population. The underlying cause is a viral infection such as Epstein-Barr virus, Coxsackie virus, parainfluenza virus, vaccine-related virus, cytomegalovirus and hepatitis B virus. http://www.wrongdiagnosis.com/g/gianotti_crosti_syndrome/basics.htm
Just what are some of the other causes of Gainotti-Crostini? provided via http://www.wrongdiagnosis.com/g/gianotti_crosti_syndrome/causes.htm
Human immunodeficiency virus (HIV) infection
Acute infection with the HIV retrovirus typically causes a generalized maculopapular rash. Other signs and symptoms include a fever, malaise, a sore throat, and a headache. Lymphadenopathy and hepatosplenomegaly may also occur. Most patients don’t recall these symptoms of acute infection.
Kaposi’s sarcoma is characterized by purple or blue papules or macules of vascular origin on the skin, mucous membranes, and viscera. These lesions decrease in size with firm pressure and then return to their original size within 10 to 15 seconds. They may become scaly and ulcerate with bleeding.
Multiple variants of Kaposi’s sarcoma are known; most individuals are immunocompromised in some way, especially those with HIV or acquired immunodeficiency syndrome. Human herpes virus-8 has been strongly implicated as a cofactor in the development of Kaposi’s sarcoma.
Discrete, flat, angular or polygonal, violet papules, commonly marked with white lines or spots, are characteristic of lichen planus. The papules may be linear or coalesce into plaques and usually appear on the lumbar region, genitalia, ankles, anterior tibiae, and wrists. Lesions usually develop first on the buccal mucosa as a lacy network of white or gray threadlike papules or plaques. Pruritus, distorted fingernails, and atrophic alopecia commonly occur.
A maculopapular rash that resembles rubella is an early sign of mononucleosis in 10% of patients. The rash is typically preceded by a headache, malaise, and fatigue. It may be accompanied by a sore throat, cervical lymphadenopathy, and fluctuating temperature with an evening peak of 101° to 102° F (38.3° to 38.9° C). Splenomegaly and hepatomegaly may also develop.
For most flu sufferers, the list of complaints includes fever, malaise, a sore throat, and a headache.
This week, University of B.C. researchers led a team of scientists that have found the swine flu vaccine triggers antibodies that protect against many flu viruses including the lethal bird-flu strain. The results support the idea there is a way to develop universal flu vaccines which would eliminate the need for seasonal vaccines each year, said UBC professor John Schrader. http://www.vancouversun.com/health/Swine+vaccine+could+protect+against+many+viruses+researchers+find+with+video/6585380/story.html#ixzz1uNhF8Vld
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